Linzess (linaclotide) is a relatively new medication, designed to ease constipation while reducing abdominal pain in individuals who have irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC). A handful of patients may buy Linzess for off-label use in treating similar conditions.

In the USA, EU, and Asia, patients buy Linzess by its brand name; it is not widely available as a generic. This will likely change as patents expire.

What to Expect from Treatment

Linzess works entirely in the intestine, where it increases fluid secretion into the intestine while decreasing the sensitivity of pain-detecting nerves. It is technically not a laxative, and there are no known gut-motility issues associated with long-term use.

The medication comes in capsules. Ideally capsules are swallowed, but they must not be chewed. Those who have difficulty swallowing can open capsules and mix them in water or soft foods, such as applesauce. Again, these mixtures should not be chewed. Water mixtures may also be administered via gastrostomy tube.

Capsules are taken once per day, ideally in the morning about 30 minutes prior to the first meal of the day.

To treat irritable bowel syndrome with constipation (IBS-C):

• The standard dose is 290 mcg once per day.

And to treat chronic idiopathic constipation (CIC):

• The standard dose is 145 mcg once per day.

Patients should not exceed 290 mcg per day; do not take a double-dose if a dose is missed.

It will take about a week of regular use to see improvements, and may take six weeks for full benefit. Patients taking the medication for CIC generally have faster results than those taking it for IBS-C, though there are exceptions.

Patients can expect to have easier, more frequent, and more complete bowel movements while also experiencing reduced or eliminated abdominal pain. Unfortunately it doesn't work for everyone; those who don't notice much difference after a few weeks of treatment should discuss alternatives with a doctor rather than continue to buy Linzess.

Precautions & Adverse Reactions

One of the most important things patients planning to buy Linzess should know is that the medication can produce diarrhea, sometimes severely so. In most (but not all) cases severe diarrhea will start in the first two weeks of treatment; if severe, treatment should end until speaking with a doctor. Mild, infrequent diarrhea is not cause for concern.

In studies, young animals given Linzess often died of dehydration. For this reason the medication is contraindicated in patients under age 6, and for those age 7 to 17 use is not recommended as effects are unclear. Effects on unborn or nursing infants are also unknown and use is discouraged while pregnant or breastfeeding.

Side effects are uncommon, and usually mild and not cause for concern:

• Diarrhea
• Gas
• Stomach distention
• Stomach discomfort

Rarely some individuals pass blood in stools. If this happens, treatment should end until a doctor can be consulted.

Linzess should not be used in individuals who have a bowel blockage.

Buy Linzess without Leaving Home

Kiwi Drug is New Zealand's oldest and most-trusted online pharmacy. Our world-class customer care and expedited ordering system ensures the purchasing process is discreet, fast, and hassle-free from any location. We utilize state-of-the-art security software to ensure your data is kept safe, and we will never share your information with any third parties.

A prescription is needed to buy Linzess from Kiwi Drug. If you don't have one, our online doctor may be able to issue one to qualifying clients; simply add the desired product to your cart, begin checkout, and answer the questions on the following page. There is no charge for our online doctor services.

Patients who already have a prescription to buy Linzess will be provided with options to transfer it to us after completing checkout.

If you have any questions or need help with your order, please don't hesitate to let us know. We're here to help!